Rubber vs. Silly Putty: Extracellular matrix viscoelasticity and its impact on cells

28 Mar
Topics in Bioengineering
Ovi Chaudhuri- Stanford University
Tuesday, March 28, 2017 -
11:45am to 12:45pm
Geological Museum 102, Haller Hall

The extracellular matrix is a complex assembly of structural proteins that provides physical support and biochemical signaling to cells in tissues. Over the last decade, studies have revealed the important role that extracellular matrix elasticity plays in regulating a variety of biological processes in cells. However, tissues and matrix are often viscoelastic. This talk will focus on our recent efforts to elucidate the viscoelastic properties of extracellular matrices, and understand how matrix viscoelasticity regulates cartilage matrix deposition by chondrocytes and breast cancer cell invasion.