Rigidity & rheology in sickle cell disease: a fertile connection

2 May
Topics in Bioengineering
Dr. Frank Ferrone
Tuesday, May 2, 2017 -
11:45am to 12:45pm
Geo Museum- Haller Hall 102

Sickle cell disease is characterized by red cells that rigidify in the absence of oxygen, as a consequence of the polymerization of the hemoglobin that fills the cells.   We will show how the polymerization mechanism is intimately related to measured mesoscopic rheological properties.   This allows a refined understanding of the disease as well as providing novel ways to diagnose its presence.