Susan X. Hsiong
PhD Candidate
shsiong@deas.harvard.edu

Education

University of Michigan, Ann Arbor, MI
M.S. in Chemical Engineering, May 2003
Ph. D. Candidate, Chemical Engineering

University of California, Berkeley, CA
B.S. Chemical Engineering, December 2000

Research Focus

Cell adhesion to extracellular matrix (ECM) ligands mediates important cellular processes such as migration, proliferation and differentiation. Thus, the ability to understand and precisely control cell-ligand interactions is critical for successful tissue engineering applications. My research focuses on understanding cell-ligand interactions which are important for the rational design of biomaterials. Specifically, I am investigating how the nanoscale spatial presentation of RGD adhesion ligands influences cell function and whether the cell response is dependent on the stage of cell commitment or differentiation.

Publications

• Hsiong, S., Mooney, D., Regeneration of vascularized bone, Periodontology 2000, 2006, 41, p. 109-22.
• Comisar, W., Hsiong, S., Kong, H.J., Mooney, D., Linderman, J., Multi-scale modeling to predict ligand presentation within RGD nanopatterned hydrogels, Biomaterials, 2005, 27(10): p. 2322-9.
• Lee, K.Y., Alsberg, E., Hsiong, S., Comisar, W., Linderman, J., Ziff, R., Mooney, D., Nanoscale adhesion ligand organization regulates osteoblast proliferation and differentiation, Nanoletters, 2004. 4(8): p. 1501-6.
• Simmons, C., Alsberg, E., Hsiong, S., Kim, W., Mooney, D., Dual growth factor delivery and controlled scaffold degradation enhance in vivo bone formation by transplanted bone marrow stromal cells, Bone, 2004. 35(2): p. 562-9.
• Murphy, W., Hsiong, S., Richardson, T., Simmons, C., Mooney, D., Effects of a bone-like mineral film on phenotype of adult human mesenchymal stem cells in vitro, Biomaterials, 2004. 26(3): p. 303-10.