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Wyss Institute Seminars

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Co-opting Moore’s Law

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Advances in Imprint Lithography for the Design of Vaccines, Therapeutics and Interfacially Active Colloids

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Environmental Health Concerns of Nanoparticles & Cut Lung Slices

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A Novel Model for Drug Discovery and Target Validation

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RNA Mimics of GFP

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Biological engineering of genetically encoded fluorescent RNA and RNA devices

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Biomechanical Modeling of the Heart

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From Multi-scale Multi-physics Formulations to Patient-specific Simulations

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Magnetically and Bacteria-Actuated Mobile Micro-Robots

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Wyss-invited lecturer Metin Sitti from Carnegie Mellon University will present miniature mobile robots with tens or hundreds of micrometer overall sizes and various locomotion capabilities, discuss significant challenges regarding actuation and power sources and propose two alternative approaches to solve the challenges.

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WYSS: Engineering DNA as an Innovative Polymer

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Our research focuses on engineering DNA as an innovative polymer -- using DNA as both genetic (bio) and generic (nano) materials. More specifically, inspired by synthetic polymers and combined with molecular biology’s tool kits, we have engineered DNA into different topological structures, all in bulk-scale. Our DNA-based structures and materials included dendrimer-like DNA, DNA nanobarcodes, DNA networks and hydrogels, DNA-basedliposomes (DNAsomes), and DNA-organized nanoparticles. From these DNA materials, we are exploringreal-world applications in diagnostics, cell-free protein production, synthetic cells, drug delivery, and novel optoelectronics.

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