Read the latest updates on coronavirus from Harvard University. For SEAS specific-updates, please visit SEAS & FAS Division of Science: Coronavirus FAQs

Course Listing

For a snapshot of courses being offered by Harvard School of Engineering over the next four years, visit our Muliti Year Course Planning tool.

Physics of Sports

ENG-SCI 20R
2022 Fall

Kelly Miller
Tuesday, Thursday
2:15pm to 3:30pm

This project-based course will introduce the physical concepts that can be applied to various human athletic endeavors. Students will focus on analyzing the dynamics of a specific sport/ physical activity through a project that they develop. This will allow students to construct physical models with an increasing level of realism that can used to analyze sporting events. Mathematics is the language of physics, and its use will be ever-present throughout the semester. However, we will focus more on the application of the laws of physics to understand the world of athletics. Students will learn the use of motion trackers and sensors to analyze motion in its dynamical and kinematic aspects.

Course Website

Flavor Molecules of Food Fermentation: Exploration and Inquiry

ENG-SCI 24
2023 Spring

Pia Sorensen
Monday, Wednesday
1:30pm to 2:45pm

Microorganisms produce a diverse array of specialized small molecules as part of their metabolic processes. In this course we will study the production, properties, and characterization of these molecules through the lens of food fermentation. In particular, we will focus on the small molecules that contribute taste and aroma in fermented foods. Students will experience the scientific inquiry process in a creative way by designing and implementing their own research project based on a fermented food of their choosing. Still a field with much potential for discovery, interested students are invited to continue their research project in the summer.

Course Website

Introduction to Electrical Engineering

ENG-SCI 50
2023 Spring

Marko Loncar
Tuesday, Thursday
12:45pm to 2:00pm

The main course objectives are to introduce students to the exciting and powerful world of electrical engineering and to explain how gadgets that we use every day actually work. After taking ES 50, you will be able to leverage the power of electricity to build systems that sense, control and program the physical world around you. Examples include intelligent and autonomous systems (robots), audio amplifiers (e.g. guitar amp), interactive art installations, light-shows, mind-controlled machines, and so on.

Course Website

Computer-Aided Machine Design

ENG-SCI 51
2023 Spring


Monday, Wednesday, Friday
11:15am to 12:30pm

An introductory course in the design, fabrication, and assembly of mechanical and electromechanical devices. Topics include: Engineering graphics and tolerances; Structural design and material selection; Machine elements and two-dimensional mechanisms; DC motors; Design methodology. Emphasis on hands-on work and team design projects using professional solid modeling CAD software and numerically controlled machine tools.

Course Website

Quantitative Physiology as a Basis for Bioengineering

ENG-SCI 53
2022 Fall

Linsey Moyer, Jennifer Lewis
Monday, Wednesday, Friday
11:15am to 12:30pm

This course is designed as an introduction to thinking as a bio/biomedical engineer and is recommended for first years and sophomores but open to all students. Simple mathematical models are used to represent key aspects of organ systems function. Core engineering concepts are explored through mechanical and electrical examples within the human body. The primary focus is on quantitative descriptions of organ systems function and control in terms of physical principles and physiologic mechanisms. It includes a foundation in human organ systems physiology, including cardiovascular, pulmonary, and renal systems. Emphasis will be given to understanding the ways in which dysfunction in these systems gives rise to common human disease processes.

Course Website

Entrepreneurship and Innovation: Practical and Academic Insights

ENG-SCI 94
2023 Spring

Josh Lerner
Monday, Wednesday
12:45pm to 2:00pm

Entrepreneurship is increasingly transforming our society and economy. This course aims to provide for undergraduates an introduction to entrepreneurship and its implications for innovation. The class will primarily consist of case study discussions, but will include some traditional lecture sessions that build on academic papers to provide more frameworks. As such, it draws primarily on materials from the introductory MBA course at Harvard Business School, “The Entrepreneurial Manager” (TEM). Students will be expected to come to class prepared to discuss the cases.

Course Website

Entrepreneurship and Innovation: Practical and Academic Insights

ENG-SCI 94
2023 Spring

Josh Lerner
Monday, Wednesday
11:15am to 12:30pm

Entrepreneurship is increasingly transforming our society and economy. This course aims to provide for undergraduates an introduction to entrepreneurship and its implications for innovation. The class will primarily consist of case study discussions, but will include some traditional lecture sessions that build on academic papers to provide more frameworks. As such, it draws primarily on materials from the introductory MBA course at Harvard Business School, “The Entrepreneurial Manager” (TEM). Students will be expected to come to class prepared to discuss the cases.

Course Website

Startup R & D

ENG-SCI 95R
2022 Fall

Paul Bottino
Tuesday
3:45pm to 6:30pm

Students do field-based work in entrepreneurship to develop their existing startup and explore new ideas and opportunities for startup creation. The course is for student-founders seeking to advance their innovation experience in a supportive community of peer founders. Students may work individually; teams with a working history are preferred. Requires self-directed, independent work and active outreach to mentors, customers, and partners for guidance and feedback in addition to that provided by the instructor and teaching staff.  Students share their work regularly and engage in a peer-to-peer feedback forum. Coursework is customized to the needs of each student and their startup role and includes development of product, technology, market, business, organization and leadership. See: https://tech.seas.harvard.edu/rad to apply for instructor permission to enroll.

Course Website

Startup R & D

ENG-SCI 95R
2023 Spring

Paul Bottino
Tuesday
3:00pm to 5:45pm

Students do field-based work in entrepreneurship to develop their existing startup and explore new ideas and opportunities for startup creation. The course is for student-founders seeking to advance their innovation experience in a supportive community of peer founders. Students may work individually; teams with a working history are preferred. Requires self-directed, independent work and active outreach to mentors, customers, and partners for guidance and feedback in addition to that provided by the instructor and teaching staff.  Students share their work regularly and engage in a peer-to-peer feedback forum. Coursework is customized to the needs of each student and their startup role and includes development of product, technology, market, business, organization and leadership. See: https://tech.seas.harvard.edu/rad to apply for instructor permission to enroll.

Course Website

Engineering Problem Solving and Design Project

ENG-SCI 96
2022 Fall

Samir Mitragotri, David Mooney
Monday, Wednesday
9:45am to 12:30pm

Semester-long team-based project providing experience working with clients on complex multi-stakeholders real problems. Course provides exposure to problem definition, problem framing, qualitative and quantitative research methods, modeling, generation and co-design of creative solutions, engineering design trade-offs, and documentation/communication skills. Ordinarily taken in the junior year.

Course Website

Engineering Problem Solving and Design Project

ENG-SCI 96
2023 Spring

Robert D. Howe, Kelly Miller
Monday, Wednesday
12:45pm to 3:30pm

Semester-long team-based project providing experience working with clients on complex multi-stakeholders real problems. Course provides exposure to problem definition, problem framing, qualitative and quantitative research methods, modeling, generation and co-design of creative solutions, engineering design trade-offs, and documentation/communication skills. Ordinarily taken in the junior year.

Course Website

Engineering Design Projects

ENG-SCI 100HFA
2022 Fall

Frank Keutsch
Thursday
2:15pm to 3:30pm

Individual engineering design projects which demonstrate mastery of engineering knowledge and techniques. Each student will pursue an appropriate capstone project which involves both engineering design and quantitative analysis. This culminates in a final oral presentation and final report/thesis. Students must complete both parts of this course, fall and spring, in order to receive credit.

Course Website

Engineering Design Projects

ENG-SCI 100HFB
2023 Spring

Frank Keutsch
Thursday
2:15pm to 3:30pm

Individual engineering design projects which demonstrate mastery of engineering knowledge and techniques. Each student will pursue an appropriate capstone project which involves both engineering design and quantitative analysis. This culminates in a final oral presentation and final report/thesis. Students must complete both parts of this course, fall and spring, in order to receive credit.

Course Website

Humanitarian Design Projects

ENG-SCI 105HFR
2022 Fall

Chris Lombardo
Tuesday
6:00pm to 7:15pm

Multi-year long team projects that provide an engineering experience working with partner communities on real-world problems. Projects provide exposure to problem definition, quantitative analysis, modeling, generation of creative solutions utilizing appropriate technology, engineering design trade-offs, and documentation/communication skills. These projects will be implemented with our project partners after the appropriate design and approvals have been obtained.

Course Website

Humanitarian Design Projects

ENG-SCI 105HFR
2023 Spring

Chris Lombardo
Tuesday
6:00pm to 7:15pm

Multi-year long team projects that provide an engineering experience working with partner communities on real-world problems. Projects provide exposure to problem definition, quantitative analysis, modeling, generation of creative solutions utilizing appropriate technology, engineering design trade-offs, and documentation/communication skills. These projects will be implemented with our project partners after the appropriate design and approvals have been obtained.

Course Website

Introduction to Scientific Computing

ENG-SCI 111
2022 Fall

Sarah Iams
Tuesday, Thursday
10:30am to 11:45am

Many science and engineering problems don’t have simple analytical solutions or even accurate analytical approximations. Scientific computing can address certain of these problems successfully, providing unique insight. This course introduces some of the widely used techniques in scientific computing through examples chosen from physics, chemistry, biology, computer science and other fields. The purpose of the course is to introduce methods that are useful in applications and research and to give the students hands-on experience with these methods. The main programming language will be Python.

Course Website

Thermodynamics by Case Study

ENG-SCI 112
2023 Spring

Scot Martin
Monday, Wednesday
12:00pm to 1:15pm

Fundamental concepts and formalisms of conservation of energy and increase of entropy as applied to natural and engineered environmental and biological systems. Pedagogical approach is to start with real-world observations and applications, extracting the underlying fundamentals of thermodynamics from these.

Course Website

Mathematical Modeling

ENG-SCI 115
2023 Spring

Zhiming Kuang
Tuesday, Thursday
10:30am to 11:45am

Abstracting the essential components and mechanisms from a natural system to produce a mathematical model, which can be analyzed with a variety of formal mathematical methods, is perhaps the most important, but least understood, task in applied mathematics. This course approaches a number of problems without the prejudice of trying to apply a particular method of solution. Topics drawn from biology, economics, engineering, physical and social sciences.

Course Website

Introduction to the Mechanics of Solids

ENG-SCI 120
2023 Spring

Joost Vlassak
Tuesday, Thursday
10:30am to 11:45am

A first course in the mechanical sciences which introduces elements of continuum mechanics and explains how materials and structures stretch, bend, twist, shake, buckle, and break. Stress-strain behavior of materials. Statically determinate and indeterminate structures. Stress and strain, equations of motion or equilibrium, strain-displacement relations. Torsion. Beam theory with applications to beam deflections, vibrations, and buckling. Three laboratory sessions required.

Course Website

Introduction to Optimization: Models and Methods

ENG-SCI 121
2022 Fall

Margo Levine
Monday, Wednesday, Friday
9:00am to 10:15am

Introduction to basic mathematical ideas and computational methods for solving deterministic optimization problems. Topics covered: linear programming, integer programming, branch-and-bound, branch-and-cut. Emphasis on modeling. Examples from business, society, engineering, sports, e-commerce. Exercises in AMPL, complemented by Mathematica or Matlab.

Course Website

Introduction to Fluid Mechanics and Transport Processes

ENG-SCI 123
2023 Spring

Petros Koumoutsakos
Monday, Wednesday, Friday
9:00am to 10:15am

Panta rhei; Energy and Entropy; Atomistic-Mesoscale-Continuum Fluids and Flows; Dimensional Analysis; Atomistic descriptions of Liquids, Gases and their interfaces;  Atomistic, Mesoscale, Continuum descriptions of Diffusion Processes; Surface Tension: bubbles and droplets; Fluid kinematics; Eulerian and Lagrangian descriptions; Macroscale conservation laws for incompressible flows; Mass conservation and potential flows; Momentum conservation and the Navier-Stokes equations; Vorticity and Vortices; Lift and Drag in Aerodynamics; Flows in Pipes and Channels; Elementary concepts of Turbulent flows.

Course Website

Mechanical Systems

ENG-SCI 125
2022 Fall

Boris Kozinsky
Tuesday, Thursday
10:30am to 11:45am

Modeling and analysis of mechanical systems. Topics include 3D rigid body dynamics, resonance, damping, frequency response, Laplace transform methods, Lagrange's equations, multiple degree-of-freedom systems and an introduction to control and continuous systems. Analytical modeling will be supplemented with numerical simulations and lab experiments. Laboratory exercises will explore vibration, and stabilization using data acquisition systems.

Course Website

Computational Solid and Structural Mechanics

ENG-SCI 128
2023 Spring

Katia Bertoldi
Monday, Wednesday
10:30am to 11:45am

Introduction to finite element methods for analysis of steady-state and transient problems in solid and structural mechanics. Implementation of simple MATLAB codes and use of existing general-purpose software (ABAQUS). Final project offers opportunities to extend focus to fluid mechanics and heat transfer and to explore additional software (e.g. COMSOL, FEniCS), if desired.

Course Website

Innovation in Science and Engineering: Conference Course

ENG-SCI 139
2022 Fall

David Weitz
Tuesday, Thursday
1:30pm to 2:45pm

Explores factors and conditions contributing to innovation in science and engineering; how important problems are found, defined, and solved; roles of teamwork and creativity; and applications of these methods to other endeavors. Students receive practical and professional training in techniques to define and solve problems, and in brainstorming and other individual and team approaches.

Course Website

Probability with Engineering Applications

ENG-SCI 150
2023 Spring

Na Li
Tuesday, Thursday
12:45pm to 2:00pm

This course introduces the fundamentals of probability theory for parameter estimation and decision making under uncertainty. It considers applications to information systems as well as other physical and biological systems. Topics include: discrete and continuous random variables, conditional expectations, Bayes’ rules, laws of large numbers, central limit theorems, Markov chains, Bayesian statistical inferences, and parameter estimations.

Course Website

Applied Electromagnetism

ENG-SCI 151
2022 Fall

Donhee Ham
Monday, Wednesday
3:00pm to 4:15pm

Electromagnetism and its applications in science and technology. Topics: Maxwell's equations; electromagnetic waves (e.g., light, microwaves, etc.); wave propagation through media discontinuity; transmission lines, waveguides, and microwave circuits; radiation and antennae; interactions between electromagnetic fields and matters; optics of solids; optical devices; origin of colors; interference and diffraction; lasers and masers; nuclear magnetic resonance and MRI; radio astronomy; wireless networking; plasmonic wave (charge density wave).

Course Website

Circuits, Devices, and Transduction

ENG-SCI 152
2022 Fall

Gage Hills
Monday, Wednesday
12:45pm to 2:00pm

This course introduces the fundamentals of circuit theory for the analysis of electrical circuits and the fundamentals of semiconductor devices for the understanding of transistors circuits and other useful actuators and sensors (i.e., transducers). Building on the principles from these two core fundamental areas of electrical engineering, the analog behavior of electronic circuits and physical devices will be modelled, analyzed, and applied. Lab assignments will focus on the design, implementation, and measurement of analog electronic circuits using real electrical components which interface to the physical world. This course complements and forms the basis for many of the abstractions that are used in digital computing systems such as in COMPSCI 141, COMPSCI 146, and COMPSCI 148.

Course Website

Electronic Devices and Circuits

ENG-SCI 154
2023 Spring

Gu-Yeon Wei
Monday, Wednesday
3:45pm to 5:00pm

Design of electronic analog circuits using semiconductor transistors. Topics include: operational amplifiers and op-amp circuits; time and frequency domain analysis of electric circuits (RC, RL, and RLC); basic semiconductor physics; PN junctions and diodes; bipolar junction transistors (BJT); Field-effect transistors (MOSFETs); bias circuits and current sources; single-ended, differential, single- and multi-stage MOSFET amplifiers; amplifier gain and bandwidth; frequency response, feedback, noise, and stability.

Course Website

Systems and Control

ENG-SCI 155
2022 Fall

Na Li
Monday, Wednesday
11:15am to 12:30pm

This course and its follow-on course ENG-SCI 156 concern the fundamentals of information systems in the real world. Together they provide a comprehensive foundation in signal processing, systems design and analysis, control, and communications, while also introducing key linear-algebraic concepts in the context of authentic applications. The first course, ENG-SCI 155, focuses on the basic principles of feedback and its use as a tool for inferring and/or altering the dynamics of systems under uncertainty. Topics include linear algebra, the elemental representations of dynamic systems, stability analysis, the design of estimators (e.g., Kalman Filter) and feedback controllers (e.g., PID and Optimal Controller). The class includes both the practical and theoretical aspects of the topic.

Course Website

Signals and Communications

ENG-SCI 156
2023 Spring

Flavio du Pin Calmon
Tuesday, Thursday
11:15am to 12:30pm

This course is a follow-on to ENG-SCI 155 and continues to develop the fundamentals of information systems in the real world. It focuses on the analysis and manipulation of signals in the time and frequency domains in the context of authentic applications. Topics include: the sampling theorem, convolution, and linear input-output systems in continuous and discrete time. Further, students are introduced to transforms—including Fourier, discrete cosine, wavelet, and PCA / SVD ‘transforms’—that map between vector spaces via matrix multiplication as a method to ease analysis provided conditionalized knowledge. Randomness, noise, and filtering. Waves and interference in the context of communications; antennae, phasors, modulation, multiplexing. Applications in communications and data science.

Course Website

Biological Signal Processing

ENG-SCI 157
2022 Fall

Demba Ba
Tuesday, Thursday
11:15am to 12:30pm

This is the first course on Biological Signal Processing, the science of collection, representation, manipulation, transformation, storing of biological signals, and the use of modern scientific computing tools (Python, Jupyter notebooks) to interpret biological signals and tell engaging and informative stories using biological data. The signals of interest can be deterministic, semi-periodic, transient, random, stationary, non-stationary, etc., depending on their source and generation mechanism. We will use EEG, EKG, temperature data, neural spiking data, and data from Covid-19 as examples. Our focus will be on foundational signal processing concepts that can be applied in a variety of biological applications. Examples include the Fourier Transform, Principal Component Analysis, Clustering, etc. Applications include those to patient monitoring, diagnostics, patient prognostics, online monitoring, and the computation of wellness measures. For many of us, one frustrating aspect of Covid-19 is our inability to understand figures that are reported, such as infection rates and numbers. We will introduce you to a powerful suite of mathematical and scientific computing tools will enable you to evaluate and make decisions based on evidence and data.

Course Website

Introduction to Robotics

ENG-SCI 159
2022 Fall

Justin Werfel
Tuesday, Thursday
11:15am to 12:30pm

Introduction to computer-controlled robotic manipulators. Topics include coordinate frames and transformations, forward and inverse kinematic solutions to open-chain manipulators, the Jacobian, dynamics and control, and motion planning. In addition, special topics will be introduced such as computer vision, soft robotics, surgical robots, MEMS and microrobotics, and biomimetic systems. Laboratory exercises will provide experience with industrial robot programming and robot simulation and control.

Course Website

Introduction to Microelectromechanical Systems

ENG-SCI 176
2022 Fall

Fawwaz Habbal
Tuesday, Thursday
12:00pm to 1:15pm

The goal of this multidisciplinary course is to enable students to learn how to create miniaturized devices. In addition to the weekly lectures, hand-on activities will lead students to become capable of creating micro-nano devices. Students will understand the physics of sensors and actuators, become familiar with thin-film fabrication technologies, and understanding how these concepts were commercialized. Learning is in small teams – together, students design, simulate, build, edit, discuss, and critique their work. Students will make basic structures using lithography, deposition, and etching. Next, they integrate such structures to create, testable, devices. At the end of the semester, they reverse-engineer some commercial devices and reflect on their fabrication and function.

Course Website

Microfabrication Laboratory

ENG-SCI 177
2023 Spring

Evelyn Hu
Monday
9:00am to 11:45am

The course provides introduction to micro- and nano-fabrication processes used to realize photonic, electronic and mechanical devices. Lectures will introduce the state-of-the-art semiconductor fabrication processes, including lithography, deposition of metals and dielectrics, etching, oxidation, implantation, and diffusion of dopants. The fabrication component of the course will be carried out in a state-of-the-art cleanroom in the Center for Nanoscale Systems, where students will fabricate several electronic and photonic devices, including transistors, light-emitting diodes (LEDs), lasers and optical resonators.  Device characterization will be performed in a state-of-the-art teaching labs in SEC in Allston.  

Course Website

Engineering Thermodynamics

ENG-SCI 181
2022 Fall

Aidin Panahi
Monday, Wednesday, Friday
1:30pm to 2:45pm

Introduction to classical engineering thermodynamics. Topics: Zeroth Law and temperature. Properties of single-component gases, liquids, and solids. Equations of state for ideal and simple nonideal substances. First Law, heat and heat transfer, work, internal energy, enthalpy. Second Law, Third Law, entropy, free energy, exergy. Heat engines and important engineering applications such as refrigerators, power cycles. Properties and simple models of solutions. Phase and chemical equilibrium in multicomponent systems; chemical potential. Electrochemistry, batteries, fuel cells. Laboratory included.

Course Website

Introduction to Heat Transfer

ENG-SCI 183
2023 Spring

David Clarke
Tuesday, Thursday
12:45pm to 2:00pm

The macroscopic description of the fundamentals of heat transfer and their application to practical problems in energy conversion, electronics and living systems with an emphasis on developing a physical and analytical understanding of conductive, convective and radiative heat transfer. Emphasis will be given to problem solving skills based on applying governing principles, mathematical models and physical intuition.

Topics include: steady state heat conduction in 1, 2 and 3D; transient heat conduction in 1D and 3D; introduction to convective heat transfer, forced convection as well as free convection; heat exchange analysis and design; elements of radiative heat transfer. There will be an emphasis on physical basis of heat transfer with mathematical description where appropriate, as well as using commercially available computer COMSOL software. Course includes (i) classes and problem sets, (ii) COMSOL simulations and (iii) a semester-long, multi-disciplinary team project.

 

Course Website

Introduction to Materials Science and Engineering

ENG-SCI 190
2023 Spring

Xin Li
Tuesday, Thursday
9:00am to 10:15am

Introduction to the structure, property, and application of materials. Crystal structure and defects. Structure property relation and crystal symmetry. Phase transformation, phase diagram, diffusion. Principles and examples for a variety of engineering applications of electrical, optical, and especially energy storage and conversion materials.

Course Website

Materials Selection and Design

ENG-SCI 192
2022 Fall

David Clarke
Tuesday, Thursday
12:45pm to 2:00pm

The repertory of materials available to engineers today and embodied in engineering systems includes tens of thousands of different materials, as well as naturally occurring ones. This course addresses why specific materials are selected for particular applications and the rational basis for their selection. The course is intended to serve as an introduction to the principles and methodology of selecting materials for engineering components based on the functionality and purpose of the component in different system applications and operating environments. The selection specification includes satisfying a variety of objectives, such as minimizing weight, cost (financial as well as environmental), end of life recycling and material scarcity.

Course Website

Foundations of Quantum Mechanics

ENG-SCI 200
2022 Fall

Federico Capasso, Kang-Kuen Ni
Monday, Wednesday
1:30pm to 2:45pm

This course is an introduction to the foundations of quantum mechanics, with specific focus on the basic principles involved in the control of quantum systems. Experimental foundations of quantum mechanics. Superposition principle, Schrödinger’s equation, eigenvalue and time dependent problems, wave packets, coherent states; uncertainty principle. One dimensional problems: double well potentials, tunneling and resonant tunneling; WKB approximation. Hermitian operators and expectation values; time evolution and Hamiltonian, commutation rules, perturbation theory, transfer matrix and variational methods. Crystals, Bloch theorem, superlattices.  angular momentum, spin, Pauli matrices and Pauli equation. Coherent interaction of light with two-level systems.  quantization of the EM field, spontaneous and stimulated emission; elements of cavity QED; Qubits, entanglement, teleportation, Bell inequalities.

Course Website

Decision Theory

ENG-SCI 201
2023 Spring

Demba Ba
Tuesday, Thursday
11:15am to 12:30pm

ES 201/AM 231 is a course in statistical inference and estimation from a signal processing perspective. The course will emphasize the entire pipeline from writing a model, estimating its parameters and performing inference utilizing real data.  The first part of the course will focus on linear and nonlinear probabilistic generative/regression models (e.g. linear, logistic, Poisson regression), and algorithms for optimization (ML/MAP estimation) in these models. We will play particular attention to sparsity-induced regression models, that arise for instance in compressed sensing, because of their relation to artificial neural networks, the topic of the second part of the course.  The second part of the course will introduce students to the nascent and exciting research area of  generative models of deep networks called model-based deep learning. At present, we lack a principled way to design artificial neural networks, the workhorses of modern AI systems. Moreover, modern AI systems lack the ability to explain how they reach their decisions. In other words, we cannot yet call AI explainable or interpretable which, as a society, poses important questions as to the responsible use of such technology. Model-based deep learning provides a framework to develop and constrain neural-network architectures in a principled fashion. We will see, for instance, how neural-networks with ReLU nonlinearities arise from sparse probabilistic generative models introduced in the first part of the course. This will form the basis for a rigorous recipe we will teach you to build interpretable deep neural networks, from the ground up. We will invite an exciting line up of speakers. Speakers will suggest papers that a group of students will present at the beginning of lecture, which will build up to a final project/paper that utilizes/on model-based deep learning applied to problems of interest to students.

Course Website

Drug Delivery

ENG-SCI 221
2023 Spring

Samir Mitragotri
Tuesday, Thursday
9:45am to 11:00am

Methods to deliver molecules to the human body. Physiological obstacles and engineering solutions. Characterization techniques for drug delivery synthesis and in vitro analysis. Case studies of current pharmaceutical products.

Course Website

Advanced Cellular Engineering

ENG-SCI 222
2022 Fall

Kit Parker
Tuesday, Thursday
11:15am to 12:30pm

This is a combined introductory graduate/upper-level undergraduate course that focuses on examining modern techniques for manipulating cellular behavior and the application of these techniques to problems in the biomedical and biotechnological arenas. Applications in drug discovery, regenerative medicine, and cellular agriculture will be discussed. Topics will include controlling behavior of cells through cell-matrix interactions, cytoskeletal architecture, and cell behavior in processes such as angiogenesis and wound healing. Lectures will review fundamental concepts in cell biology before delving into topical examples from current literature. Students will work weekly in the lab learning cell culture techniques, soft lithography, microscopy, and classical in vitro assays measuring cell behavior.

 

Course Website

Neuroengineering

ENG-SCI 225
2022 Fall

Jia Liu
Tuesday, Thursday
12:45pm to 2:00pm

This course provides an introduction to biological neural systems, and current engineering efforts to understand, control, and enhance the function of neural systems. The focus is on the basic knowledge of molecular basis, anatomic structures, and electrical functions of central and peripheral nervous systems, and the most state-of-the-art genetic/genomic, optical, electrical, magnetic, and computational tools for nervous systems. Key themes throughout the course will include structures of central and peripheral nervous systems, genetic engineering, RNA sequencing, optogenetics, microscope, bioelectronics, MRI, and computational neuroscience. This includes both the practical and theoretical aspects of the topic.

Course Website

Medical Device Design

ENG-SCI 227
2023 Spring

Conor Walsh, Linsey Moyer
Monday, Wednesday
2:15pm to 3:30pm

Project-based course on the design of medical devices to address needs identified by hospital-based clinicians. Students work in teams with physicians to develop a novel device. The design process includes: needs finding; problem identification; prior art searches; strategy and concept generation; estimation; sketching; sketch modeling; machine elements, ergonomics and prototyping.

Course Website

Computational Solid and Structural Mechanics

ENG-SCI 228
2023 Spring

Katia Bertoldi
Monday, Wednesday
10:30am to 11:45am

Introduction to finite element methods for analysis of steady-state and transient problems in solid and structural mechanics. Implementation of simple MATLAB codes and use of existing general-purpose software (ABAQUS). Final project offers opportunities to extend focus to fluid mechanics and heat transfer and to explore additional software (e.g. COMSOL, FEniCS), if desired.

Course Website

Survey of Energy Technology

ENG-SCI 229
2023 Spring

Michael Aziz
Wednesday, Friday
3:00pm to 4:15pm

Principles governing energy generation and interconversion. Current and projected world energy use. Selected important current and anticipated future technologies for energy generation, interconversion, storage, and end usage.

Course Website

Advanced Tissue Engineering

ENG-SCI 230
2023 Spring

David Mooney
Monday, Wednesday
3:45pm to 5:00pm

Fundamental engineering and biological principles underlying field of tissue engineering, along with examples and strategies to engineer specific tissues for clinical use. Student design teams prepare a research proposal and participate in a weekly laboratory.

Course Website

Energy Technology

ENG-SCI 231
2023 Spring

Michael Aziz
Wednesday, Friday
3:00pm to 4:15pm

Principles governing energy generation and interconversion. Current and projected world energy use. Selected important current and anticipated future technologies for energy generation, interconversion, storage, and end usage.

Course Website

Water, Weather and Climate

ENG-SCI 233
2022 Fall

Kaighin McColl
Monday, Wednesday
4:30pm to 5:45pm

This course provides a graduate-level introduction to the global hydrologic cycle and relevant terrestrial and atmospheric processes. It covers the concepts of water and energy balance; atmospheric radiation, composition and circulation; precipitation formation; evaporation and vegetation transpiration; dynamics of the atmospheric boundary layer (ABL), and its coupling with the land surface; boundary layer clouds; atmospheric chemistry within the ABL; and groundwater flow and unsaturated zone processes.

Course Website

Technology Venture Immersion

ENG-SCI 234
2023 Spring

Conor Walsh

Using a learning-by-doing approach, student teams will work on their own venture concepts in this intensive immersion course. The course will convey concepts and builds skills required in early stage technology ventures, including problem finding (human-centered design, customer discovery), solution finding (ideation methods, prototyping, user testing), business model validation (hypothesis generation, minimum viable products, lean experimentation), sales and marketing methods, venture financing, and team building and leadership skills. Enrollment limited to first-year MS/MBA: Engineering Sciences students only.

Course Website

Technological Innovation and Entrepreneurship

ENG-SCI 236
2023 Spring

Woodward Yang
Thursday
6:45pm to 8:45pm

This course will explore the complex relationships between scientific advances, technological innovations, manufacturing technologies, and the development and evolution of an industry. While many students may already be familiar with scientific research and technological innovations, this course will explore how advances in science and technology impact manufacturing, industry architecture, and business. Some basic background in business management and government will be reviewed including manufacturing processes, business strategy, disruptive innovation, intellectual property, industry standards, and political economy to provide proper context for understanding the practical implications of technological innovations. We will review and investigate the basic scientific phenomena and technological innovations that underpin some major industries such as Steel, Automobiles, Semiconductors and Personal Computers. By reviewing the historical evolution of these technologies and the corresponding economic, political, legal, and sociological circumstances, we will develop a framework for understanding the strategic forces that disrupt businesses and create entrepreneurial opportunities and reshape industry structures. Working together in small groups, students will be assigned a term project to research and analyze the strategic forces that shaped other major industries such as Energy, Pharmaceuticals, Communications, and Textile/Clothing.

Course Website

Advanced Innovation in Science and Engineering: Conference Course

ENG-SCI 239
2022 Fall

David Weitz
Tuesday, Thursday
1:30pm to 2:45pm

Explores factors and conditions contributing to innovation in science and engineering; how important problems are found, defined, and solved; roles of teamwork and creativity; and applications of these methods to other endeavors. Students receive practical and professional training in techniques to define and solve problems, and in brainstorming and other individual and team approaches.

Students are expected to meet all the requirements of Engineering Sciences 139 and in addition are required to prepare an individual term project with significant analytic emphasis in an area of scientific or technological innovation.

Course Website

Solid Mechanics

ENG-SCI 240
2022 Fall

Joost Vlassak
Tuesday, Thursday
1:30pm to 2:45pm

Foundations of solid mechanics, development of elasticity theory, and introduction to  linear visco-elasticity and plasticity. Basic elasticity solutions. Variational principles. Deformation of plates. Introduction to large deformation.

Course Website

Solid Mechanics: Advanced Seminar

ENG-SCI 242R
2022 Fall

Katia Bertoldi
Tuesday
9:00am to 11:45am

Nonlinear finite elements for solids and structures. The key goal of this class is the application of the finite element method for analysis of steady-state and transient nonlinear problems in solid and structural mechanics. Implementation of simple MATLAB codes and use of existing general-purpose software (ABAQUS). Topics include the implementations of user-defined subroutines (UHYPER, UMAT, VUMAT, MPC and UEL), instability analyses, analysis of waves propagation.

Course Website

Fracture Mechanics

ENG-SCI 247
2023 Spring

Zhigang Suo
Monday, Wednesday
1:30pm to 2:45pm

Fundamentals of fracture with applications in materials and structural mechanics. Micromechanics of fracture in ceramics, metals, and polymers. Fracture of composite materials. Interfacial fracture mechanics. Fatigue crack propagation.

Course Website

Advanced Neural Control of Movement

ENG-SCI 249
2023 Spring

Maurice Smith
Tuesday, Thursday
11:15am to 12:30pm

Students expected to meet all of the requirements of Biomedical Engineering 130 (formerly Engineering Sciences 149) and in addition to submit a term project with significant analytic content.

Course Website

Information Theory

ENG-SCI 250
2022 Fall

Flavio du Pin Calmon
Monday, Wednesday
12:45pm to 2:00pm

Fundamental concepts of information theory, Entropy, Kullback-Leibler divergence, Mutual information; typical sequences and their applications, Loss-less data compression, Huffman codes, Elias Codes, Arithmetic Codes, Discrete Memory-less Channels, Channel Coding and Capacity, Differential Entropy, Gaussian Channels, rate distortion theory, Multi-user Information Theory, Connections between information theory and statistics.

Course Website

Advanced Topics in Robotics Research

ENG-SCI 252R
2023 Spring

Robert Wood
Monday, Wednesday
9:45am to 11:00am

A graduate seminar course on advanced topics in robotics research. Students read and present research papers and undertake a research project.

Course Website

Mathematics of High-Dimensional Information Processing and Learning

ENG-SCI 254
2022 Fall

Yue Lu
Monday, Wednesday
9:45am to 11:00am

This course introduces students to fundamental results and recently developed techniques in high-dimensional probability theory and statistical physics that have been successfully applied to the analysis of information processing and machine learning problems. Discussions will be focused on studying such problems in the high-dimensional limit, on analyzing the emergence of phase transitions, and on understanding the scaling limits of efficient algorithms. This course seeks to start from basics, assuming just a solid understanding of undergraduate probability theory. Students will take an active role by exploring and applying what they learn from the course to their own research problems.

Course Website

Informal Robotics/New Paradigms for Design and Construction

ENG-SCI 256
2023 Spring

Chuck Hoberman

This course teaches how to create original robotic devices made of light, compliant – informal – materials.

New fabrication techniques are transforming the field of robotics. Rather than rigid parts connected by mechanical connectors, robots can now be made of folded paper, carbon laminates or soft gels. They can be formed fully integrated from a 3D printer rather than assembled from individual components. Informal Robotics draws on cutting-edge research from leading labs, in particular, Harvard’s Micro Robotics Laboratory which has created unique designs for ambulatory and flying robots, end-effectors, medical instruments and other applications.

We will explore informal robotics from multiple perspectives, culminating with the design of original devices displaying animated intelligence in real-time. Going beyond traditional engineering approaches, we will also explore new opportunities for design at the product, architectural, and urban scales.

Techniques:
Hands-on:  Working with the GSD’s Fab Lab we are creating a kit of parts that will be available to all enrolled students. With the kit, you can create a wide range of folding mechanisms controlled by on-board miniature electronics. 

Software / Simulation: Software workshops will be offered on Fusion 360 and Grasshopper to simulate robotic performance within a virtual environment. 

Topics:
- Kinematics: design techniques for pop-ups, origami, and soft mechanisms.
- Fabrication: methods: for composite materials, laminated assembly, self-folding, and integrated flexures - the kit of parts will allow for hands-on exploration.
- Controls: how to actuate movement and program desired behavior. Topics include servos, linear actuators, and use of Arduino actuator control.
- Applications: takes us beyond purely technological concerns, contextualizing Informal Robotics within larger trends where materials, manufacturing and computation are starting to merge.

Format, prerequisites, evaluation:

A portion of the lecture material will be pre-recorded, allowing students to view this on their own schedule. The class session will emphasize discussion and review of assignments & projects. 

There will be assignments to produce test mechanisms and CAD models, followed by final group projects. Presentations and discussions of ongoing student work are integral to the course. There are no prerequisites and evaluation will be based on completion of assignments and the final project.

Projects may be virtual, physical or both. Resources for fabricating customized final projects are not fully known at this point, but I am committed to supporting physical-making to the degree possible.

Course Website

Introduction to Bioelectronics

ENG-SCI 258
2023 Spring

Jia Liu
Monday, Wednesday
11:15am to 12:30pm

This course introduces bioelectronics and its applications in neuroscience, neuroengineering, cardiology, wearable technology, and so on. The focus is on the basic principles of bioelectricity, biochemistry, and physiological behaviors of biological systems and how to design electronic tools to precisely measure and control them. Key themes throughout the course will include bioelectricity, biochemistry, cellular and tissue physiological behavior, optogenetics, sensors, stimulators, circuits, signal processing, electronics-biology interface, and applications. This includes both the practical and theoretical aspects of the topic. Three experimental demonstrations will be included as part of the normal class meeting time. Given its broad coverage, students who enroll in this course are expected to have a substantial background in chemistry, biology, and electrical engineering (see recommended prep and course requirements). The contents and course requirements are similar to those of Biomedical Engineering 129 (BE 129), with the exception that students enrolled in Engineering Sciences 258 (ENG-SCI 258) are expected to undertake a substantial course project.

Course Website

Advanced Introduction to Robotics

ENG-SCI 259
2022 Fall

Justin Werfel
Tuesday, Thursday
11:15am to 12:30pm

Introduction to computer-controlled robotic manipulators. Topics include coordinate frames and transformations, forward and inverse kinematic solutions to open-chain manipulators, the Jacobian, dynamics and control, and motion planning. In addition, special topics will be introduced such as computer vision, soft robotics, surgical robots, MEMS and microrobotics, and biomimetic systems. Laboratory exercises will provide experience with industrial robot programming and robot simulation and control.

Course Website

Topics in Mixed-Signal Integrated Circuits

ENG-SCI 271R
2022 Fall

Gu-Yeon Wei
Thursday
3:45pm to 6:30pm

A seminar course that dives into research and development of various topics in integrated circuits and systems for low-power and/or high-performance computing. The course in Spring 2021 will focus on recent advances in novel devices, circuits, and systems that have been developed for machine learning and AI tasks and applications.

Course Website

Optics and Photonics

ENG-SCI 273
2022 Fall

Marko Loncar
Monday, Wednesday
3:00pm to 4:15pm

The focus is on the foundations of optics/photonics and on some of its most important modern developments and applications. Powerful and widely used computational tools will be developed in the sections. Topics to be covered: Maxwell's equations, Free space optics. Reflection, refraction, polarization (Jones Calculus and Stokes parameters); interference and diffraction. Light-matter interaction, dispersion and absorption. Guided wave optics (including optical fibers). Perturbation and couple mode theory, transfer matrix methods; numerical methods. Optical resonators.  Photonic crystals. Near-field optics. Metal optics and Plasmonics. Metamaterials and Metasurfaces.

Course Website

Introduction to Microelectromechanical Systems

ENG-SCI 276
2022 Fall

Fawwaz Habbal
Tuesday, Thursday
12:00pm to 1:15pm

The goal of this multidisciplinary course is to enable students to learn how to create miniaturized devices. In addition to the weekly lectures, hand-on activities will lead students to become capable of creating micro-nano devices. Students will understand the physics of sensors and actuators, become familiar with thin-film fabrication technologies, and understanding how these concepts were commercialized. Learning is in small teams – together, students design, simulate, build, edit, discuss, and critique their work. Students will make basic structures using lithography, deposition, and etching. Next, they integrate such structures to create, testable, devices. At the end of the semester, they reverse-engineer some commercial devices and reflect on their fabrication and function.

Course Website

Microfabrication Laboratory

ENG-SCI 277
2023 Spring

Evelyn Hu
Monday
9:45am to 11:45am

The course provides introduction to micro- and nano-fabrication processes used to realize photonic, electronic and mechanical devices. Lectures will introduce the state-of-the-art semiconductor fabrication processes, including lithography, deposition of metals and dielectrics, etching, oxidation, implantation, and diffusion of dopants. The fabrication component of the course will be carried out in a state-of-the-art cleanroom in the Center for Nanoscale Systems, where students will fabricate several electronic and photonic devices, including transistors, light-emitting diodes (LEDs), lasers and optical resonators.  Device characterization will be performed in a state-of-the-art teaching labs in SEC in Allston. 

Course Website

Designing Technology Ventures

ENG-SCI 280
2022 Fall

Robert D. Howe, Thomas Eisenmann
Monday, Wednesday
3:45pm to 5:00pm

This is a core course for students in the MS/MBA: Engineering Sciences program. The course will begin with methods for modeling engineering and business systems, including discrete and continuous systems and feedback controls. Students will write simple simulations and then use professional modeling software to simulate complex systems. Students will next learn design methodology, including stakeholder modeling, ideation, and decision making tools. A final team project will involve design of a system, including simulation and prototyping.

Course Website

Design Theory and Practice

ENG-SCI 285
2022 Fall

Elizabeth Christoforetti, Roberto Verganti

Any organization, business or venture grounds its value on how "meaningful" are its products (functionally, symbolically and emotionally). Design Theory and Practice (DTP) empowers students to create products that are meaningful, to people who use them and to society at large. The course has three purposes:

1. To inspire students about the power of design in new business creation. We will address questions such as: Why is design relevant in tech ventures? How does it create value? And, most of all, why is it fundamental for a technology entrepreneur/leader?

2. To enable them to move into action, by learning the theories and practice (mindsets, processes, methods) of design: Where do ideas come from? How to frame (and especially re-frame) a problem? How to understand what is meaningful to users? How to make a product desirable (functionally, emotionally and symbolically)? How to design and build the user interface of a product? How to test it? How to narrate and visualize a novel idea?

3. To co-explore, with the class and the instructor, the use of design as a leadership practice: How does a leader who masters design can better contribute to creation of value? How can we forge a new manifesto for leadership, inspired by design?

The course is intensively project-based. Students will work in teams on a complex innovation challenge proposed by a real corporation. They will suggest a more effective framing of the problem, and create a novel meaningful solution, with a special focus on the user interface.

Course Website

Launch Lab/Capstone 1

ENG-SCI 292A
2023 Spring

Russell J Wilcox, Alan Maccormack

The MS/MBA Capstone is an intensive project that requires teams of students to apply and integrate the skills they have learned across core disciplines developed in the program curriculum. Specifically, teams will be expected to design, build and launch a new technology-based product/service venture, and thereby to demonstrate mastery with respect to three areas of knowledge: Design Knowledge: The use of human-centered design methods to understand users, identify solutions to their needs, and gather feedback via rapid, iterative prototyping. Technical Knowledge: The use of rigorous system engineering methods to plan, design, develop, build, and test a complex technology-based product/service, integrating knowledge across multiple engineering disciplines. Business Knowledge: The use of business model analysis and lean experimentation methods to develop and test a set of hypotheses that capture how the new product/service will create value, including business model design, pricing, sales and marketing, operating model and profit formula.

The Capstone is divided into two parts, the first of which is an immersive course completed during the January term of the G2 year (Capstone I). The subsequent spring course (Capstone II) follows on from and builds upon work completed in January. Given students prior coursework, a working knowledge of human-centered design methods, systems engineering techniques, and business modeling and lean experimentation is assumed. Launch Lab therefore focuses on the practical application of these skills to team projects, supplemented by content in three areas: i) seminars on advanced methods and techniques, ii) workshops that demonstrate how to put these skills and tools into practice, and iii) guest speakers who share their experience in the areas of design, technology and business.
 

Course Website

Launch Lab/Capstone 2

ENG-SCI 292B
2023 Spring

Russell J Wilcox, Alan Maccormack
Monday
4:00pm to 6:00pm

The MS/MBA Capstone is an intensive project that requires teams of students to apply and integrate the skills they have learned across core disciplines developed in the program curriculum. Specifically, teams will be expected to design, build and launch a new technology-based product/service venture, and thereby to demonstrate mastery with respect to three areas of knowledge: Design Knowledge: The use of human-centered design methods to understand users, identify solutions to their needs, and gather feedback via rapid, iterative prototyping. Technical Knowledge: The use of rigorous system engineering methods to plan, design, develop, build, and test a complex technology-based product/service, integrating knowledge across multiple engineering disciplines. Business Knowledge: The use of business model analysis and lean experimentation methods to develop and test a set of hypotheses that capture how the new product/service will create value, including business model design, pricing, sales and marketing, operating model and profit formula.

The Capstone is divided into two parts, the first of which is an immersive course completed during the January term of the G2 year (Capstone I). The subsequent spring course (Capstone II) follows on from and builds upon work completed in January. Given students prior coursework, a working knowledge of human-centered design methods, systems engineering techniques, and business modeling and lean experimentation is assumed. Launch Lab therefore focuses on the practical application of these skills to team projects, supplemented by content in three areas: i) seminars on advanced methods and techniques, ii) workshops that demonstrate how to put these skills and tools into practice, and iii) guest speakers who share their experience in the areas of design, technology and business.
 

Course Website

Professional Writing for Scientists and Engineers

ENG-SCI 297
2022 Fall

Daniel Needleman, Suzanne Smith
Thursday
3:00pm to 5:00pm

This class leads students to develop their skills in the critical reading and writing of science and engineering. Genres will include research articles, grant proposals, school/fellowship/job applications, or lay abstracts & press releases for the non-scientific public. Crucially, students will be empowered not only to achieve their own writing goals, but also to break down these learned skills and impart them to others, as effective collaborators and mentors of younger students.

Course Website

Professional Writing for Scientists and Engineers

ENG-SCI 297
2023 Spring

Jenny Hoffman, Suzanne Smith
Wednesday
3:00pm to 5:00pm

This class leads students to develop their skills in the critical reading and writing of science and engineering. Genres will include research articles, grant proposals, school/fellowship/job applications, or lay abstracts & press releases for the non-scientific public. Crucially, students will be empowered not only to achieve their own writing goals, but also to break down these learned skills and impart them to others, as effective collaborators and mentors of younger students.

Course Website

Methodologies in Design Engineering

ENG-SCI 298DR
2023 Spring

Kit Parker
Friday
9:45am to 12:30pm

This is a SAT/UNSAT seminar course focused on design thinking, analysis, planning, and executing the development of engineered systems. Weekly meetings will include discussions and assigned readings of case studies and examples of the systems surrounding the developing technical system. Organizing and executing research, innovation, and product design at the scales from academic group, to startup, to major industry will be discussed. The course is designed to allow the engineer and designer to integrate technical knowledge into an executable framework as an individual or leader of a design team.

Course Website

Solving Tech's Public Dilemmas

ENG-SCI 298R
2022 Fall

Ash Carter
Monday, Wednesday
1:30pm to 2:45pm

This course identifies and analyzes alternative solutions to the dilemmas that disruptive technology is posing to public good in the digital, biotech, and jobs and training domains. The objective is for students to craft technologically-informed practical public-private approaches to some of the key policy issues of our time. It begins with a brief history of successful and unsuccessful governance of far-reaching technological changes in the past. The first part of the course treats the ongoing digital revolution, crafting solutions to issues of social media responsibility, cybersecurity, and artificial intelligence (AI).  It then turns to the biotech revolution that is gathering momentum, addressing genome editing, bioweapons and bioterror, and the role of venture capital in biotech. The third segment of the course addresses the ways that technology is disrupting the nature of work and lifelong training. The example of driverless cars will be used to illustrate the challenges and opportunities that technology provides to sustain cohesive and prosperous societies in the era of tech "disruption". Assignments stress the development of key writing and speaking skills.

Course Website

Special Topics in Engineering Sciences

ENG-SCI 299R
2022 Fall

Joost Vlassak

Supervision of experimental or theoretical research on acceptable problems in engineering and applied science and supervision of reading on topics not covered by regular courses of instruction.

Course Website

Special Topics in Engineering Sciences

ENG-SCI 299R
2023 Spring

Joost Vlassak

Supervision of experimental or theoretical research on acceptable problems in engineering and applied science and supervision of reading on topics not covered by regular courses of instruction.

Course Website